Labial melanotic macule Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome In the process of removing a Labial Melanotic Macule. A Labial Melanotic Macule is a well defined, oval, brown to black, flat patch on the central third of the lower lip, as seen What Caused These Multiple Hyperpigmented Macules of the Mouth? Pigmented macular lip lesion Clinical Advisor